Go into your Tron 2.0 folder - probably "C:\Program Files\Buena Vista Interactive\Tron 2.0", might also be "Program Files (x86)" - look for a file named launchcmds.txt, and delete it. Then try running the TRON 2.0 game launcher (not the Mod Manager) and play the game.
If you're still getting errors, then it's starting to sound like the CD or image you used to install the game is somehow corrupt.